Therapeutics

Latest Innovations

Electronic Tuning Of Site Selectivity For Complex Molecule Synthesis

 

Researchers from the University of Illinois have developed a method for selectively derivatizing complex natural molecules such as Amphotericin B. The technology...

Less Toxic Amphotericin B Derivative

 

Researchers at the University of Illinois have developed a derivative of Amphotericin B that likely has a lower toxicity than the popular fungicide. The...

New Drugs for Malarial and Bacterial Infections

 

New anti-infectives are required now more than ever as resistance to existing drugs increases in prevalence. Enzymes unique to bacteria or parasites are potential...

Genes for the Biosynthesis of Plantazolicin, a Molecule Effective in Killing Bacillus Anthracis

 

Anthrax disease, caused the by the bacterium Bacillus anthracis, is a major bioterrorism threat. Currently, B. anthracis infections are treated with various broad...

Therapeutic Scheme for Human Basigin

 

Cancer researchers are focusing their efforts on identifying central pathways that trigger or enhance the invasiveness of tumor cells. One such target is EMMPRIN...

Compounds That Selectively Induce Cancerous Cell Death in the G1 Phase of the Cell Cycle

 

Malignant melanoma is a cancer that is refractory to current chemotherapeutic treatments. The average survival time for patients is 6 months. This coupled with...

Compounds for the Treatment of Fluoquinolone resistant infections

 

Researchers from the University of Illinois have synthesized a variety of compounds with strong activity toward fluoroquinolone resistant bacteria. These...

Powerful Biphosophonates for Treatment of Cancer, Bone Loss, and Infectious Disease

 

Although there are already a few existing compounds for use in the treatment of bone diseases, these new compounds may have efficacy exceeding that of current...

A Novel Treatment for Fragile X Synaptic and Cognitive Deficits

 

Dr. Galvez from the University of Illinois explores a promising direction for understanding the underlying mechanisms behind Fragile X Syndrome-related...

Biosynthesis of Lantibiotics: In vitro semi-synthetic production methods for generation of industrial antibiotic, Lacticin 481

 

This invention allows the engineering of semi-synthetic lantibiotics to a much larger extent than using typically practiced in vivo methods. The method is the...

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