Therapeutic Cargo Delivery System for Treatment of Botulism Paralysis


Dr. Brenda Wilson has developed an anti-toxin that can be used for treatment of botulism. The botulinum toxin causes dangerous paralysis of motor neurons that can lead to breathing complications. Existing anti-toxin therapy only works on toxins circulating in the bloodstream and not on cells that are already intoxicated with botulinum toxin. Dr. Wilson's invention can specifically treat botulinum-intoxicated neurons and can neutralize the toxin intracellularly. In vivo experiments in a mouse model have shown treatment with the anti-toxin can reverse botulism paralysis. This invention has the potential to speed recovery for individuals suffering from the devastating effects of botulism intoxication.